Global Whole Exome Sequencing Market Growth (Status and Outlook) 2019-2024

Exome sequencing is a capture based method developed to identify variants in the coding region of genes which affect protein function. While exome capture methods using PCR, hybrid capture and molecular inversion probes exist, the most common and efficient strategies are in-solution capture methods. In-solution capture utilizes pools of oligonucleotides or probes bound to magnetic beads, whose sequence has been designed to hybridize to exon regions. After binding to genomic DNA, these probes are pulled down and washed, allowing exon regions to be selectively sequenced. While there are approximately 180,000 exons in the human genome, constituting less than 2% of total sequence, the exome contains ~80-90% of known disease causing variants making it a cost-effective alternative to whole genome sequencing. When performing exome-seq, users should not only consider average on-target coverage but also the local coverage of particular sites of interest. When choosing between exome and whole genome sequencing (WGS), consider that exome sequencing has the advantage that oligonucleotides are designed to particular genomic regions where typical coverage with WGS is not enough for SNP calling. It is also more affordable enabling the analysis of more individuals and populations. With WGS, you can detect variants in regions not covered by exome capture allowing or the identification of structural and non-coding variants associated with disease. The consumption of whole exome sequencing has exceeded 120 K samples per year. Whole exome sequencing is mainly produced by American companies. M ...
Table of Contents 2019-2024 Global Whole Exome Sequencing Market Report (Status and Outlook) 1 Scope of the Report 1.1 Market Introduction 1.2 Research Objectives 1.3 Years Considered 1.4 Market Research Methodology 1.5 Economic Indicators 1.6 Currency Considered 2 Executive Summary 2.1 World Market Overview 2.1.1 Global Whole Exome Sequencing Market Size 2019-2024 2.1.2 Whole Exome Sequencing Market Size CAGR by Region 2.2 Whole Exome Sequencing Segment by Type 2.2.1 Agilent HaloPlex 2.2.2 Agilent SureSelect 2.2.3 Agilent SureSelect QXT 2.2.4 Illumina TruSeq Exome 2.2.5 Roche Nimblegen SeqCap 2.2.6 MYcroarray MYbaits 2.3 Whole Exome Sequencing Market Size by Type 2.3.1 Global Whole Exome Sequencing Market Size Market Share by Type (2019-2024) 2.3.2 Global Whole Exome Sequencing Market Size Growth Rate by Type (2019-2024) 2.4 Whole Exome Sequencing Segment by Appli ...
7395

9618

OUR CLIENT